DRUM: Understanding Neuroplastic Effects of Transcranial Direct Current Stimulation through Analysis of Dynamics of Large-Scale Brain Networks

We’ll have to wait until June 2013 to read the dissertation however.

…Results from Study 1 using model-free analysis showed that a specific fronto-parietal network at rest was modulated up to a period of 30 minutes outlasting the duration of the stimulation. Further model-based analysis of this fronto-parietal network showed that these differences were driven by network activity primarily involving high frequency gamma band connectivity to and from the supplementary motor area to associated regions left primary motor cortex stimulated region, left prefrontal and parietal cortices. Results from Study 2 showed that the tDCS exerts highly polarity-specific effects on the impact of oscillatory network connectivity, within the functionally relevant fronto-parietal network, on behavioral changes associated with motor learning. These results advance our understanding of neuroplasticity mediated by tDCS and thus, have implications in the clinical use of tDCS for enhancing efficacy of neurorehabilitation in patients with stroke and traumatic brain injury.

URI: http://hdl.handle.net/1903/12741

via DRUM: Understanding Neuroplastic Effects of Transcranial Direct Current Stimulation through Analysis of Dynamics of Large-Scale Brain Networks.

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