Mike Weisend | FutureTech Podcast

Mike Weisend – Treating the Brain from the Outside
We met Michael Weisend back in podcast #4 (March 2013!) and have been following along ever since. In this interview Mike discusses what he’s been up to at Rio Grande Neurosciences. What caught my ear especially were the discussion around ‘closed-loop TES’, where EEG information informs when and where to stimulate with TES. Also, his discussion of personalized disposable bio-degradeable electrodes was interesting. Mike closes the interview with an invitation to anyone knowing how to engineer an ‘EEG amplifier’ that would allow for the separation of EEG data and active TES stimulation, to contact him. (mike.weisend [theAtSign] riograndneurosciences.com). Kudos to Richard Jacobs for an interesting interview.

Transcranial Electrical Stimulation: A Stimulating Discussion of Current Research

In the third section of his talk (around 30 minute mark), Dr. McConnell discusses an experiment they are working on that uses EEG to monitor sleep, and according to their protocol, turn on a TES device (tACS-like) in order to induce slow wave EEG activity. The practical application is improved memory consolidation in Alzheimer’s patients. Very interesting!

Published on May 14, 2017 Neurology Grand Rounds 3 May 2017 – Transcranial Electrical Stimulation: A Stimulating Discussion of Current Research.

Brice McConnell, MD, PhD
Instructor/Fellow, Neurology
University of Colorado

Sooma tDCS

Finnish company Sooma manufactures and supports a tDCS device for the treatment of depression (in Europe). They recently added clearance to treat pain in Canada, and I would assume, are aggressively working towards clearing their device for the treatment of depression in Canada and the U.S.

I would recommend muting the sound (captioned so not necessary) in these next two.

DIY tDCS YouTube Catch Up

If you follow the blog you’ll know I’m not savvy enough in the ways of electronics to know a well-constructed DIY circuit when I see it. I’ve generally depended on the Reddit crowd to sort through the pros and cons of DIY tDCS circuit design. Now that there are a handful of professionally developed and readily available devices on the market, I’m not seeing as many DIY projects, but here’s a couple that popped up on Youtube in the last week or so.

DIY tDCS Secrets Revealed! Brain Hacking stancurtin


tDCS DIY Device Tutorial NeuoHacking

Brain Stimulation | AirmanMagazineOnline

  Published on Mar 13, 2017
Dr. Andy McKinley is the leader of the Non-Invasive Brain Stimulation (NIBS) Team in the Cognitive Performance Optimization Section, Applied Neuroscience Branch, Warfighter Interface Division, Human Effectiveness Directorate at Wright-Patterson Air Force Base.
AirmanMagazineOnline Youtube Channel
See Also: Super SEALs: Elite Units Pursue Brain-Stimulating Technologies (Military.com)

Gamma Waves Enhance the Brain’s Immune System to Treat Mice with Alzheimer’s disease.

Foc.us v2 40hz tACS

I was first alerted to the story from a December 7 article in the Guardian, “Strobe lighting provides a flicker of hope in the fight against Alzheimer’s“. Researchers from the Picower Institute for Learning and Memory at MIT, working with (let’s call them) ‘Alzehiemer’s mice’, had discovered that flashing a light at 40hz (on-off at 40 times per second) increased gamma wave oscillations in the brain which led to the reduction of Amyloid beta (think, plaque) through the activation of microglia ‘clean-up’ immune cells. Here, let them explain it!

The paper, Gamma frequency entrainment attenuates amyloid load and modifies microglia makes clear that the light-flickering affected the visual cortex, which makes sense, as the light reaches the brain through the eyes. But wait, thinks I, what about tACS (transcranial Alternating Current Stimulation)… haven’t I seen numerous papers implying the ability to ‘entrain’ brain waves with tACS? What if you could increase 40hz Gamma in other parts of the brain? (Google Scholar Search: transcranial alternating, entrain, gamma)
But then I discovered that Radiolab just covered this exact story and it’s totally amazing! Really a must listen. So fun to hear the researcher’s amazement at this accidental (sort of) discovery!
So what’s with the photo of the Foc.us v2 device set up for a 40hz tACS session? Just that…

More about The Picower Institute for Learning and Memory at MIT

Extreme DIY – Transcranial Electrical Stimulator, Arduino Compatible | quicksilv3rflash

According to Instructables/reddit user quicksilv3rflash…

This device can be used for any kind of human electrical stimulation, such as tDCS, tACS, tRNS, or tVNS. Its hardware, when properly constructed and tested, limits output current such that -2.1mA < output_current < +2.1mA , based on the 2mA safety limit recommended in these published guidelines.

Transcranial Electrical Stimulator, Arduino Compatible
Discussion on Reddit Clear instructions to build a precision computer-controlled tACS/tDCS/tRNS device, <$100
Build a Human Enhancement Device (Basic TDCS Supply)
Simple TACS for Analogue Electromancers

LED headset shows promise for Alzheimer’s, brain injuries | CITY News

Full Story: LED headset shows promise for Alzheimer’s, brain injuries | CITY News
This device/protocol is new to me, though I have been looking into Low Laser Light Therapy which looks promising. I will be looking into the science around this device, also its history, i.e. which came first, the device or the science.

Lew Lim, the founder and CEO of VieLight is seen explaining the device in the video.

The technology is called transcranial and intranasal photobiomodulation (PBM). Initial, small-scale results, are promising.

Five people, with mild to moderate Alzheimer’s, used the headsets every day for 12 weeks. The headset frame, with four different LED cluster-heads and an LED that clips to the inside of the nostril, was turned on for 15 minutes a day.

After the three months, neuroscientists noticed some patients, who were not able to speak in full sentences, could now put sentences together. Patients also experienced improved sleep and reduced wandering.

Sorry about the ad in the embedded video!

Paper: Significant Improvement in Cognition in Mild to Moderately Severe Dementia Cases Treated with Transcranial Plus Intranasal Photobiomodulation: Case Series Report

The device is called VieLight, (which does not include EEG which was used in the study depicted), seems to be available for sale. A smaller device, called the ‘Pocket Miracle’ is also for sale.

Zapping Your Brain at Home to Cure Fatigue | The Atlantic

Using remote rehabilitation to administer tDCS to MS patients.
Zapping Your Brain at Home to Cure Fatigue

Each day for two weeks, Bennett would don a headband equipped with moistened sponges and attached to what she called a “big cellphone”—a tDCS stimulator. When she was ready to start the session, a clinician would give her a four-digit code to enter on a keypad, and the current would surge through the wires and into her brain.

Transcranial Direct Current Stimulation Combined With Computer Games At Home Reduces Cognitive Symptoms of Multiple Sclerosis
More about Supervised Neuromodulation: Soterix mini-CT

Caputron Announces New Version ActivaDose ll 29V 2mA Max Setting

Robin at Caputron sends word of their new ‘exclusively from Caputron’ ActivaDose 29V 2mA max Iontophoresis device. My one caveat with the ActivaDose had been the potential for user error in choosing a 4mA setting (rather than the 1 or 2mA setting traditionally used in tDCS research). This new device removes that possibility. This is the device you could confidently show your Mom how to use. The new version maintains the ActivaDose FDA approval for iontophoresis. This new version becomes the device I can recommend in all confidence, also because Caputron stands behind all the products they offer.
Readers of the blog get a generous discount on this, or any other (including GoFlow) device purchased at Caputron using promo code diytdcs at checkout.

activadose-ii-starter-kit