If you’ve been following along then most of what’s discussed in this May, 2018 lecture won’t surprise you, but it’s nicely put together and I would say, emphasizes the validation of applying stimulation while ‘doing something’ (Functional Targeting). The idea being that the stimulation then amplifies the activity of the neurons involved in the task. Though it does beg the question, What would be an appropriate task to involve a patient with in the treatment of depression? I think it’s important to note that most of what is discussed, in terms of any affects tDCS may have, remain hypothetical!
The 2019 joint meeting of Neuromodulation:The Science and NYC Neuromodulation is about to start and a page devoted to abstracts has been published. It will be updated as more info becomes available. Want a look into the future of neurostimulation? Here it is!
Dr. Brent Williams of SpeakWisdom recently published an article on the new LIFTiD tDCS device, How to Use the LIFTiD Headset for Depression Relief. The device (which is available at Caputron) has yet to be extensively reviewed but its main advantage, defined electrode placement, could also be seen as a weakness.
Do not use the “Oreo Cookie” approach where you soak your sponge in your saline solution and squeeze it to remove the extra. Because it over saturates, it’s dripping, it’s very “subjective” and hard to reproduce. Get a syringe and put 8mL of saline solution on your sponge and make sure to also get the corners. Do that prior to insert the electrode in between the 2 layers. If it’s dripping wet, that’s bad (you’re doing it wrong!). You should not have to use a tower on the patient’s neck.
Yannick Roy from NeuroTechX with Marom Bikson, chair of the Neuromodulation Conference. The interview was recorded at City College, NYC, during the Neuromodulation 2017.
Analysing these high-standard studies revealed that tDCS seems to reliably improve the symptoms of depression, addiction and craving, and fibromyalgia. It also uncovered that the technique does not work for tinnitus, and that the evidence for using tDCS for stroke rehabilitation was not as strong as many had thought.
An email from Michelle Pearson at the NIH (because I had signed up for the online version of the workshop) alerted me today to a trove of TES (Transcranial Electric Stimulation) info being made available to us. Presenter slides (in PDF form) from the workshop were available for download. Because the download process was pretty wonky, involving many clicks and declined logins to Dropbox I thought to make them available here as well.
Revisiting this post from a few months ago because as I slowly wade through these state-of-the-art brain stimulation presentations from the leading scientists in the field, I’m discovering a lot of new information that is not generally known or being discussed. For example, in this talk ‘BrainSTIM2015 – Physiology and functional effects of tDCS and related techniques’, Michael Nitsche explores why 1mA may be a better dosage choice and also how a second session of tDCS 30 minutes after the first may lead to increased plasticity effects.
Vince Clark has just published video presentations from the recent BrainSTIM conference.
This is a real treasure trove of state-of-the-art tDCS and brain stimulation information.
Presenters: Vince Clark, Giulio Ruffini, Marom Bikson, Peter Bandettini, Michael Nitsche, Katie Witkiewitz, Peter Fox, Luke Torre-Healy, Erika Ross, Mayank Jog, Abbas Babajani-Feremi, Alexander Opitz, Mark Lowe, Hiroyuki Oya, Felipe Salinas, Shalini Narayana, Branislava Curcic-Blake, Franca Tecchio, Yuranny Cabral-Calderin. https://www.youtube.com/channel/UCJXWh-KAWQdAYXZAMeH4SCg
Katie, 23, has suffered from anxiety and depression since she was 18. When her boyfriend Lee told her about transcranial directcurrent stimulation (tDCS), a form of neurostimulation which involves administering a low level of electrical current to the brain, she was sceptical. But Lee had heard that it could help people with mood disorders and wondered if she might benefit from it.
“The first time, I freaked out,” she remembers. “I thought, ‘I can’t cope with putting electrical stimulations in my brain.’ Lee put this machine on and, it’s difficult to explain, but, everything went empty in a good way. I can’t remember if I’ve ever felt like that. I felt relaxed and chilled inside. It was a mad sensation and an out-of-body experience.”
She’d tried anti-depressants in the past but found they didn’t work for her. Now she uses the kit regularly. “It’s improved my life and improved my mind,” she says.
Dr. Giulio Ruffini, “Transcranial Current Stimulation: Going Multifocal”
“…I will describe a new class of devices using multi electrode montages and small, EEG-compatible electrodes, complemented by advanced biophysical models.”
Dr. Marom Bikson, “Targeting transcranial Electrical Stimulation using EEG: The scalp space approach”
“…Next, how to optimize tES based on either evoked or spontaneous EEG recording is discussed including a novel “scalp space” approach which requires no source localization and no computational modeling.”
I see also that the The Neuroelectrics Team will be demonstrating their “latest wireless EEG (Enobio) and tCS (StarStim) technology as well as our latest StarStim Research Home Kit.
Is it safe? Obviously the test wasn’t designed to assess any possible negative cognitive effects, but apart from some, “skin tingling, itching, and mild burning sensations” the subjects tolerated frequent TES (transcranial electric stimulation) well.
In the present study, we tested the tolerability (safety) and compliance, compared to sham, of two common tES approaches having a current density < 2 mA/cm2; transcranial Direct Current Stimulation (tDCS) or transcranial Pulsed Current Stimulation (tPCS) used by healthy subjects three to five days (17 – 20 minutes per day) per week for up to six weeks in a naturalistic environment. In this study 100 healthy subjects were randomized to one of three treatment groups: tDCS (n = 33), tPCS (n = 30), or sham (n = 37) and blinded to the treatment condition. The tES and sham waveforms were delivered through self-adhering electrodes on the right lateral forehead and back of the neck. We conducted 1905 treatment sessions (636 sham, 623 tDCS, and 646 tPCS sessions) on study volunteers over a six-week period. There were no serious adverse events in any treatment condition.