Gamma Waves Enhance the Brain’s Immune System to Treat Mice with Alzheimer’s disease. v2 40hz tACS

I was first alerted to the story from a December 7 article in the Guardian, “Strobe lighting provides a flicker of hope in the fight against Alzheimer’s“. Researchers from the Picower Institute for Learning and Memory at MIT, working with (let’s call them) ‘Alzehiemer’s mice’, had discovered that flashing a light at 40hz (on-off at 40 times per second) increased gamma wave oscillations in the brain which led to the reduction of Amyloid beta (think, plaque) through the activation of microglia ‘clean-up’ immune cells. Here, let them explain it!

The paper, Gamma frequency entrainment attenuates amyloid load and modifies microglia makes clear that the light-flickering affected the visual cortex, which makes sense, as the light reaches the brain through the eyes. But wait, thinks I, what about tACS (transcranial Alternating Current Stimulation)… haven’t I seen numerous papers implying the ability to ‘entrain’ brain waves with tACS? What if you could increase 40hz Gamma in other parts of the brain? (Google Scholar Search: transcranial alternating, entrain, gamma)
But then I discovered that Radiolab just covered this exact story and it’s totally amazing! Really a must listen. So fun to hear the researcher’s amazement at this accidental (sort of) discovery!
So what’s with the photo of the v2 device set up for a 40hz tACS session? Just that…

More about The Picower Institute for Learning and Memory at MIT

Citizen Science! The Verdict Is In!

Just kidding. C’mon folks. The smallest bit of Googling… At least he doesn’t seem to have hurt himself.

NEVER connect electrodes directly to a 9 volt battery.
Sticky (TENS) electrodes are HIGHLY not recommended.

Youtuber theCharmIsGlobal 7/25/16

YouTuber theCharmIsGlobal 7/25/16

Based on his perception of the Sally Adee article/study featured on RadioLab 9-Volt Nirvana episode, YouTuber TheCharmIsGlobal attempted to replicate the experience in an experiment he called, “TDCS EXPERIMENT WITH CALL OF DUTY: BLACK OPS III” The 43 minute video is mostly onscreen playing of Call Of Duty, but he starts the video with a discussion of tDCS, applies tDCS as shown above at around 10:40, and declares victory at 42:50.

So the verdict is in, yeah, it does work! It really does work!

9-Volt Nirvana – Radiolab

In the last couple years, tDCS has been all over the news. Researchers claim that juicing the brain with just 2 milliamps (think 9-volt battery) can help with everything from learning languages, to quitting smoking, to overcoming depression. We bring Michael Weisend, neuroscientist at Wright State Research Institute, into the studio to tell us how it works (Bonus: you get to hear Jad get his brain zapped). Peter Reiner and Nick Fitz of the University of British Columbia help us think through the consequences of a world where anyone with 20 dollars and access to Radioshack can make their own brain zapper. And finally, Sally tells us about the unexpected after-effects of a day of super-charged sniper training and makes us wonder about world where you can order up a state of mind.

via 9-Volt Nirvana – Radiolab.